Obese men are more likely to develop aggressive prostate cancer and are more likely to die of their disease. Researchers at Johns Hopkins may have uncovered the explanation. Obese men have shorter telomeres. Telomeres are like aglets on shoelaces or the little tips that protect the ends of their chromosomes. Short telomeres can cause the chromosomes to become unstable and this abnormality is strongly associated with cancer. Their research in collaboration with doctors at Harvard Medical School found that men with shorter telomeres had a much higher risk of dying from prostate cancer.
Not only did obesity demonstrate shorter telomeres and who were physically inactive had even shorter telomeres compared to men of normal weight and who were the most physically active.
Bottom Line: Telomere shortening in prostate cells is associated with obesity and decreased physical activity. Therefore, this is one more reason for men to adopt a healthy lifestyle and develop good nutritional habits and get moving!