Posts Tagged ‘castration’

The Colon and the Prostate Just Got Closer-Treatment for Prostate Cancer Increases the Risk for Colon Cancer

November 13, 2010

There are hundreds of thousands of men with prostate cancer who are receiving therapy that decreases their testosterone levels either by taking injections (Eligard, Lupron, Zolodex, or Trelstar) that decrease the production of testosterone by the testicles or by having the testicles surgically removed.   These treatment options have several side effects including osteoporosis, diabetes, and heart problems.  Added to that list is the slightly increased risk of colon cancer.

A recent report from the Journal of the National Cancer Institute reported a small increase in colon cancer of 2.2% for men who have been treated with drugs to lower the testosterone level or who have had castration for the treatment of their prostate cancer compared to 1.8% of colon cancer in men who did not receive hormone deprivation treatment.

With this new revelation, men on hormone deprivation should obtain routine screening for colorectal cancer and adopting a healthy lifestyle, complete with plenty of exercise.

Bottom line: Men with prostate cancer receiving hormone deprivation need to be aware of the risks associated with this treatment which now includes a slight increase in colon cancer.