Posts Tagged ‘Viagra’

Woman Can Turn On Just Like Men-Addyi, Female Viagra

October 27, 2015

Women have been waiting for decades to catch up with men in the area of intimacy with their partners. Men have been fortunate that Viagra, Cialis, and Levitra have worked wonders for millions of American men. Today there is a female Viagra, called Addyi or flibanserin that is helping women with a decreased sexual desire.

Experts are calling Addyi, the so-called “female Viagra” that’s become the first-ever FDA-approved pill for hypoactive sexual desire disorder, a revolution for women’s sexual health.

The approval of Addyi is the most important advancement in female sexual health since the oral contraceptive was approved in 1960.

It validates women’s right to treatment for sexual problems and their right to sexual health. Let the truth be told that Addyi validates that there is as much biology as psychology with regard to women’s sexual function and this is the same for men.
Addyi also known as the “little pink pill,” doesn’t work the same way that Viagra does in men. Instead of affecting blood flow to the genitals, as Viagra does, Addyi targets certain serotonin receptors in the central nervous system within the brain —similar to how anti-depression medications target other receptors — in order to improve sexual desire.

Until Addyi there were no FDA-approved drugs that targeted low sexual desire in either men or women. The FDA’s approval of Addyi to the breakthrough in men’s sexual health research when Viagra was first approved in 1998. Before then, doctors told men that erectile dysfunction was all in their heads and the only treatment offered men was testosterone which was seldom effective. Now, in 2015, we accept that there are physical reasons such as diabetes, heart disease, and hundreds of medications that result in men not being able to obtain or sustain erections. Addyi’s introduction to the marketplace could do the same for the estimated 5.5 million to 8.6 million U.S. women suffering from hypoactive sexual desire disorder, meaning a chronic lack of interest in sex.

Addyi was originally formulated as an anti-depressant. While it failed to treat depression, researchers noticed that it did increase sexual desire. Sprout Pharmaceuticals then tested it for safety and effectiveness in more than 11,000 women before winning the recent FDA approval. In three randomized studies women who took Addyi had between one-half to one more satisfying sexual event per month on average than women who took placebo pills. It also increased sexual desire as compared to the placebo, as well as lowered distress related to sexual desire dysfunction.

Although the root causes of low sexual desire in women include relationship issues and changing hormone levels due to aging.

The drug’s side effects, which include severely low blood pressure and loss of consciousness if taken with alcohol, are comparable to the side effects of psychoactive medications that were able to win FDA approval far more easily than Addyi. The most common side effects were dizziness, sleepiness, nausea and fatigue, which is why the pill is recommended for use before bed.

Bottom Line: Women with decreased sexual desire now have a medication that may solve that problem. Addyi has now been approved by the FDA for the treatment of low sexual desire in women. For more information, speak to your physician.

ED, Viagra and Melanoma-The Jury Is Still Out

June 27, 2015

Viagra remains one of the most popular drugs for treating erectile dysfunction or ED. The drug is quite safe and has been used by millions of men world wide. Recently there was a report of a relationship between Viagra and the potentially lethal skin condition, melanoma.

A potential link between erectile dysfunction drugs and melanoma may exist, but inconsistencies in the data make a cause-and-effect relationship questionable.
Men who had a history of using phosphodiesterase type 5 (PDE5) inhibitors (Viagra, Levitra, or Cialis) had a 20% greater risk of melanoma as compared with men who never used the drugs. However, the strongest association involved men who filled a single prescription for a PDE5 inhibitor. Total number of prescriptions filled did not significantly affect melanoma risk.
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Moreover, the PDE5 inhibitor-melanoma association pertained only to early-stage disease (stage 0-I), did not differ by type of PDE5 inhibitor, and was not limited to melanoma, as an increased risk of basal cell carcinoma was seen among users of PDE5 inhibitors. This was reported online in The Journal of the American Medical Association.

The findings are consistent with those of a similar study reported a year ago. However, the previous study was based on data that showed only whether a man had ever used a PDE5 inhibitor. Extracted from the Health Professionals Follow-up Study, the data were limited to the original PDE5 inhibitor, sildenafil (Viagra), and lacked details about use of the drug, such as the number of prescriptions filled.

The study was not able to prove cause and effect relationship. A longer follow-up and more detailed assessment of the dose and frequency of Viagra use at multiple times in the would be necessary for future studies.

In theory, a causal association between PDE5 inhibitor use and melanoma has biologic plausibility. Several studies have provided evidence of interaction between PDE5 and melanoma.

A Swedish study of the 435 men who used PDE5 inhibitors and developed melanoma, 275 had filled one or more prescriptions for sildenafil and 224 had filled at least one prescription for Levitra or Cialis.

Overall, men who used PDE5 inhibitors had a slight increase for melanoma versus nonusers. The risk of melanoma did not differ significantly across the three types of ED drugs.

Bottom Line: What’s my advice. Whether you use Viagra, Levitra, or Cialis, or not, I suggest you make use of plenty of sun screen. Nothing less than a SPF of 35. Also, if you are at risk for melanoma, i.e., are light completed, have frequent exposure to sun, then see a dermatologist at least once a year for a total body examination.

ED (Erectile Dysfunction) – What About Natural Solutions? They May Be Dangerous To Your Health

March 11, 2015

ED (Erectile Dysfunction) – What About Natural Solutions?

ED is a common problem affecting over 30 million American men. For the past 10 years oral medication, Viagra, Cialis, and Levitra have been available for helping me achieve intimacy with their partners. A recent analysis by the FDA has revealed that some of the many over the counter (OTC) supplements contain the same active ingredient in Viagra but often at a higher more dangerous dose than what is prescribed by the doctor.

As reported by BuzzFeed, in the past week as many as 25 “natural supplements” meant to treat erectile dysfunction were found to contain sildenafil citrate, the same active ingredient found in prescription drugs such as Viagra.

Despite an obvious attempt at falsely advertising a prescription drug as an herbal remedy, the unregulated tainted supplements could cause serious harm and even death to those who unknowingly buy them.

Natural erectile dysfunction supplements are both one of the biggest sellers on the market for herbal treatments and one of the most likely to be tainted with unregulated ingredients. It’s suspected the FDA has only hit the tip of the iceberg regarding the current investigation into herbal erectile dysfunction.

The World Health Organization describes counterfeit drugs as a widespread problem, but it occurs most often in developing countries. For example, one study from 2012 found that around one-third of all available malaria medications sold in Asia and sub-Saharan Africa were counterfeit. A press release from the University of Michigan stated that counterfeit drugs kill around 700,000 people every year.

There is hope, though. Last year Pfizer made $1.7 billion off of Viagra sales. This large monetary stake that companies such as Pfizer have in prescription erectile dysfunction medication could be enough to push the regulation of fake drugs to priority level.

Bottom Line: There are effective drugs for treating ED. For the safety of your health and your erections, speak to your doctor or use only the medication prescribed by your physician.

Can Treatment For ED Cause Skin Cancer

June 21, 2014

A recent study has implicated Viagra as a cause of skin cancer. A study found that men who used the erection-enhancing drug sildenafil (Viagra) were 84% more likely to develop melanoma, a very significant skin cancer. That’s especially important for older men, who are at greater risk for developing melanoma and also at greater risk for dying from it. An estimated 76,000 Americans (more than half of them men) will be diagnosed with melanoma this year, and almost 10,000 will die from it.

Here are two truths about this work that you need to know. 1) This study does not show that Viagra causes skin cancer. Instead, it shows that in a large group of men, those who said they used Viagra ended up being diagnosed more often with melanoma than those who didn’t use this drug. The study shows a connection, but not a cause. 2). Even if Viagra does promote melanoma, the absolute increase is small.

The study grew out of laboratory research on how Viagra acts on cell-to-cell signaling pathways. This work demonstrated that the drug mimics key parts of a process that lets melanoma cells spread to other parts of the body. Skin cancer that spreads (metastasizes) is hard to control and can end in death.

Over the next decade, among the 29,929 men who said they had never used Viagra, 128 developed melanoma. Among the 1,618 Viagra users, 14 developed melanoma. In other words, 4.3 of every 1,000 who didn’t take Viagra developed melanoma compared to 8.6 of every 1,000 men who took Viagra.

After statistical adjustments, the increase from 4.3 to 8.6 is the 84% increase in risk that many news reports focused on. Researchers call that the relative risk (one group compared to another). The absolute increase, 4.3 cases per 1,000 men, represents an increase of 0.43%.

Whether a similar connection might exist between other erectile dysfunction drugs and melanoma isn’t known.
The raw numbers suggest that the risk for melanoma associated with Viagra is small. It’s even smaller than what was reported in the study because not all of the 14 cancers in the Viagra group can be attributed to the drug. Many factors affect a man’s risk of melanoma—the most important of which are age and cumulative exposure to ultraviolet (UV) radiation.
Should men who use Viagra worry about getting melanoma? Right now, no one can say. The relationship could be pure coincidence.
My advice to men: Protect your skin from too much sun and have routine skin checks to identify melanoma and other types of skin cancer early, while they are still treatable.

Bottom Line: In short, be afraid—but not of Viagra. Be concerned about getting too much sun and pay attention to weird-looking moles that could turn into metastatic cancer. Cover up when you go outside, and use a broad-spectrum sunscreen liberally when you do go out into the sun to work and play.

Perhaps an Over the Counter Pill For ED (Erectile Dysfunction)

June 1, 2014

Eli Lilly , the manufactures of Cialis, are requesting permission to sell Cialis, the world’s top-selling impotence drug, without a prescription.
The drug in very small daily doses is also approved to treat enlarged prostate glands.
Lilly is requesting approval to sell Cialis over the counter in the United States, Europe, Canada and Australia. It remains to be seen, however, whether regulators will allow Cialis to be sold without a prescription, in view of possible side effects and contraindications such as in men using nitroglycerin for chest pain. Cialis can cause a dangerous fall in blood pressure if taken with nitroglycerin.
The U.S. Food and Drug Administration, needs to be sure patients are able to understand complex aspects of their disease, or exactly when to take the drug to ensure safe use.
Cialis will face competition from cheaper generics in the United States in 2017, when Viagra becomes a generic prescription.
Bottom Line: ED drugs are very expensive, $25-$35 a pill. Financial help may be on the ay if the drugs become generic making the treatment of ED more affordable.

At Last: Viagra For Women

June 1, 2014

Drug makers are testing new drugs that may be able to increase sexual desire in women.
A drug to boost female sex drive could be worth billions to the first company that manages to get it approved by the FDA. Recently, two new treatments have made strides towards that goal. But some are skeptical of the real value of such a drug to the women it’s supposed to help.
In late 2004, FDA approval of Intrinsa, a testosterone patch for low female sex drive, seemed imminent. News reports heralded Intrinsa as a “Viagra for her,” suggesting that it would revolutionize sexual health for women just as erectile dysfunction pills had for men.

Except an FDA advisory panel saw things differently. Finding numerous problems with the evidence for the drug’s effectiveness and safety, experts on the panel voted against approving it. Procter & Gamble, the company responsible for Intrinsa, withdrew its application. Now the frontrunner in the race to market the first prescription drug for low female sex drive is Boehringher-Ingelheim Pharmaceuticals. It has a drug called flibanserin in phase III clinical trials, the final phase of drug testing required for FDA approval. The company is a WebMD sponsor.
Flibanserin is a bit mysterious. It is a kind of antidepressant, but it hasn’t been approved previously for any use. Boehringher-Ingelheim is saying little publicly about the drug. At the moment we are not sure how the drug works or what is the mechanism of action of flibanserin.
Another drug, called bremelanotide, is in development for low female sex drive and male erectile dysfunction. Both potential uses are being tested in clinical trials, which are early studies to assess how well a drug works and how safe it is.
Bremelanotide is a new chemical created in the laboratory. It’s given in the form of a nasal spray, and it acts on the central nervous system.
Bottom Line: Stay tuned as a pill for women suffering from sexual dysfunction may be just around the corner at a pharmacy near you.

Stendra-Viagra’s New Cousin For the Treatment of Erectile Dysfunciton

February 14, 2014

For the past decade Viagra, Levitra, and Cialis have been the mainstay of oral medications for the treatment of erectile dysfunction or impotence. There’s a new drug on the block, Stendra, whose main claim to fame will be the faster onset of action compared to the three previous drugs.

In published studies in the medical literature, Stendra has an onset of action as early as 15 minutes. The drug can be taken with food or fluids but a high fat meal reduces the rate of absorption and delays the onset of action. Duration of Stendra is the same as Viagra and Levitra at 4-6 hours. Viagra and Levitra report onset at 30 minutes to 1 hour. Cialis is about the same or a little longer, but duration of Cialis is 24-36 hours.
The response or efficacy appears to be similar as the other oral medications, i.e., Cialis, Viagra and Levitra.

The same safety precautions exist: 1) Contraindicated with the use of any nitrates such as nitroglycerin as the use of Stendra with nitroglycerin may drop the blood supply to the hear and risk a serious heart problem; 2) Caution in combination with certain prostate drugs such as Flomax or Rapaflo; 3) Seek help for erection lasting more than 4 hours although I have never seen a man with an erection lasting more than 1-2 hours with the use of any oral medication for the treatment of erectile dysfunction.

The side effects include headaches, facial flushing, nasal congestion, and back pain.

Bottom Line: If a man is looking for a faster onset of action of oral medication for the treatment of erectile dysfunction, then Stendra may be his Holy Grail!

Sex After a Heart Attack

October 3, 2013

A man has a recent heart attack. He is eager to get back in the saddle and remembers the movie, Something’s Gotta Give, when Jack Nicholson, who had a recent heart attack, asks his doctor about when “his best friend” can start getting back into action. He’s told that he has to wait until he can climb two flights of stairs without shortness of breadth or chest pain. Both the man and his partner are concerned if sex trigger could another heart attack.
It is well documented that fewer than 1% of heart attacks come from having sex. It makes sense to think of sex as a form of exercise: If your doctor clears you for physical activity, you’re also likely safe for sex. Remember the two flights of stairs test.
Most men and their partners are uncomfortable broaching the topic with their doctor. Most doctors are comfortable talking about sexual intimacy and you shouldn’t avoid the topic. Often the patient is surprised — or even relieved — that the doctor raises the subject.
Similar to any type of exercise, if you begin to feel symptoms such as chest pain, abnormal shortness of breath, fatigue, dizziness, or palpitations, it definitely makes sense to slow down what you’re doing, whether you’re a man or a woman. If you’re pretty certain it’s angina, which is temporary pain or pressure in the chest when the heart doesn’t get enough oxygen, it might help to take your nitroglycerin.
The exception to that advice is for men who use medication for erectile dysfunction such as Viagra, Levitra, and Cialis — it’s dangerous to take nitroglycerin. Your blood pressure can fall to dangerously low levels, and there’s an increased risk of heart attack and even death. If you’re on an erectile dysfunction drug and have heart-related symptoms during sex, call your doctor.
Bottom Line: Sexual intimacy is important to men at all ages and includes men who have had a recent heart attack. A candid conversation will help you get back to enjoying a sexual relationship with your significant other. Talk to your doctor

Shocking New Treatment For Impotence-Shock Waves Found Effective In Treating ED

June 16, 2013

Shock wave has been successfully used for over twenty years for the treatment of kidney stones. Now a modified shock wave has been used to treat impotence or erectile dysfunction.

A study of twenty men with an average of 50 and who had ED for more than three years were selected to participate. The men had ED on the basis of cardiovascular disease. The treatment consists of using low-intensity shock waves twice a week for three weeks. The men were tested one month later and 15 of the 20 men had significant improvement in their ability to engage in sexual intimacy with their partner.

The men were found to have an increased in blood flow to the penis when comparing the pre-treatment to the post treatment period.

Bottom Line: Yes, drugs such as Viagra, Levitra, and Cialis are effective in the treatment of ED however they only work when the man consumes the medication. Shock waves may be therapeutic and may result in such significant improvement that the man once treated no longer needs to take any medication for his ED. Stay tuned as shock wave to the penis may be just what the doctor orders!

Impotence: When You Can’t Get It Up is Getting You Down

June 3, 2013

Probably nothing devastates a man more than having a failure in the bedroom. Impotence or erectile dysfunction affects nearly 33 million men in the United States. You are not alone. Help is available for nearly every man who has erectile dysfunction.
Diet
According to the Urology Channel’s “Erectile Dysfunction: Natural/Alternative Treatments,” erectile dysfunction can be treated by eating right, drinking plenty of water and avoiding sugar, dairy and caffeine. They recommend to eat whole, fresh, unrefined and unprocessed foods, including vegetables, whole grains, soy, beans, seeds, nuts, olive oil and cold-water fish such as salmon and tuna.
Taking your vitamins can also help; the Urology Channel suggests supplements such as flaxseed, and in particular vitamins C, E and the mineral zinc. These vitamins and supplements help bolster the vascular system, which is an important part of good sexual health.


Exercise
Since sexual health relies on the vascular system, a strong heart plays an important part in treating erectile dysfunction. Aerobic exercises such as power walking, running, bicycling or dancing strengthen the cardiovascular system. A stronger cardiovascular system gives stronger support to the vascular system that supports a healthy erection.
 Kegel exercises–exercises that flex the pelvic muscle– which are helpful in strengthening the ligaments that support an erection. These exercises can also increase blood flow in the pelvic area, which can aid in achieving a strong erection.



Herbs
Herbs which are used in Traditional Chinese Medicine to support healthy erectile function include ginseng, ginger and ginkgo biloba.
 Ginseng helps increase blood circulation, and is typically taken as a dried powder, often as a paste mixed with honey. Ginkgo biloba also increases blood flow in the arteries, which help support the vascular functions that enable a healthy erection.
 Another non-medical option is garlic but the treatment can be tough to take: the trick to getting the most out of garlic is to chew fresh, uncooked garlic very thoroughly. Though it is unpleasant and can be downright painful, this allows your body to absorb powerful natural nutrients through the blood vessels in the mouth. Some of the most powerful ingredients in garlic are destroyed as they travel through the digestive system, and these erectile dysfunction-fighting nutrients are only absorbed while chewing.
One out of two men over age 40 have had difficulty attaining and maintaining an erection sufficient for sexual intercourse, doctors say. And while the numbers are smaller, even some younger men may have difficulty developing an erection.
However, more than at any other time in history, erectile dysfunction is a problem with a solution. Medications and external and internal treatments have improved dramatically, allowing thousands of men to return to healthy sexual functioning. Likewise the stigma has decreased with public awareness.
Over the past 20 years, increased media attention, scores of television ads for medications like Viagra, Levitra and Cialis and starring roles in movies and television shows have moved erectile dysfunction out of the shadows and onto the list of common health concerns.
Erectile dysfunction is often caused by a lack of adequate blood flow, which can be an indicator of a potentially life-threatening health problem such as heart disease, high cholesterol, or diabetes.
Surgeries for prostate cancer, bladder and certain colorectal cancers may result in erectile dysfunction.
Regardless of age or cause, treatment options are the same, depending on the individual.

Men with heart problems and some other health conditions cannot take Viagra, Levitra, or Cialis. These drugs can be fatal for men taking nitroglycerine or any nitrates.
The next level of treatment includes injections and vacuum pumps, both of which can be effective. While the thought of injections is less than appealing to most men, the results are excellent.
If pill and external treatments are not effective, doctors say an internal prosthetic device is an option.
An implant gives the spontaneity and quality of erection that they can’t get with many of the other treatments including pills, injections or vacuum pump. Internal devices or a penile prosthesis are effective continuously on demand, which means a man and his partner can achieve a full erection on demand and within seconds that contains itself as long as they want to have sex.
While these surgeries have been performed since the 1950s improvements in surgical technique and devices are dramatic.
The 30-minute procedure is minimally invasive and usually does not require hospital admission. Men may experience some discomfort for 1-2 days after the procedure.

Men who have the prosthesis have by far the best satisfaction rate for any treatment for erection problems, up into the 99 percent range.

Bottom Line: Erectile dysfunction affections millions of American men. There are solutions both medical and surgical that can help men restore their ability to successfully engage in sexual intimacy with their partners.